Neuropathology Case Studies

Neuropathology of supercentenarians - four autopsy case studies

Supercentenarians (aged 110 years old or more) are extremely rare in the world population (the number of living supercentenarians is estimated as 47 in the world), and details about their neuropathological information are limited. Based on previous studies, centenarians (aged 100-109 years old) exhibit several types of neuropathological changes, such as Alzheimer's disease and Lewy body disease...

Neurobiology of autism: neuropathology and neuroimaging studies.

INTRODUCTION This study performs a review of the last studies in the field of neuropathology and neuroimaging of autism. METHOD A search was done in Medline for articles on neuropathology and neuroimaging in autism and the most relevant articles of the last 10 years up to date were selected. RESULTS The existence of structural abnormalities in the brain of patients with autism, affecting di...

Fulminant demyelinating encephalomyelitis: Insights from antibody studies and neuropathology.

OBJECTIVES Antibodies to myelin oligodendrocyte glycoprotein (MOG) are detectable in inflammatory demyelinating CNS diseases, and MOG antibody-associated diseases seem to have a better prognosis despite occasionally severe presentations. METHODS We report the case of a 71-year-old patient with acute visual and gait disturbance that dramatically worsened to bilateral amaurosis, tetraplegia, an...

Dissociations in processing past tense morphology: neuropathology and behavioral studies.

Neuropsychological research showing that the regular ("jump-jumped") and irregular ("drive/drove") past tense inflectional morphology can dissociate following brain damage has been important in testing claims about the cognitive and neural status of linguistic rules. These dissociations have been interpreted as evidence for two different computational systems-a rule-based system underlying the ...

Powassan encephalitis: a case report with neuropathology and literature review.